AD/PD™ 2019, Lisbon - Abstract Topics from 2017

2017 ABSTRACT TOPICS

​Themes​Topics​Sub-Topics​

 

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​β-Amyloid Diseases
Alzheimer's Disease (AD), Prodromal AD, Cerebral Amyloid Angiopathy (CAA), Down Syndrome (DS) & Mild Cognitive Impairment (MCI)

 

 

Tauopathies
AD, Progressive Supranuclear Palsy (PSP), Corticobasal Degeneration (CBD), Pick's Disease & Chronic Traumatic Encephalopathy

 

 

α-Synucleinopathies
Parkinson's Disease (PD), PD Dementia, Dementia with Lewy Bodies (DLB), Multiple System Atrophy (MSA), Olivopontocerebellar Atrophy (OPCA)

 

 

TDP-43- and C9orf72-Related Diseases Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Lobar Degeneration (FTLD), Frontotemporal Dementia (FTD), ALS-FTD Spectrum Diseases

 


Vascular Dementia    Multi-Infarct Dementia (MID), White Matter Disease & Stroke

 

 

Prion Diseases Creutzfeldt-Jakob Disease (CJD), Fatal Familial Insomnia (FFI) & Gerstmann-Straussler-Scheinker Disease (GSSS)  

                                                           

 

Huntington's Disease (HD) & Other Neurodegenerative Disorders

 

 

Demyelinating Diseases Multiple Sclerosis (MS), Leucodystrophy

 

 

Lysosomal and Storage Diseases Gaucher, Niemann Pick etc.

 

 

Psychiatric and Epileptic Symptoms in Neurodegenerative Diseases

 

 












Patient Care & Caregiver Support

 

Disease Mechanisms, Pathophysiology

 

 

 

 

Abeta, tau, α-synuclein aggregation, misfolding, phophorylation, acetylation, modifications
LRKK2, parkin, PINK1, DJ-1
​C​ell to cell transmission, spreading of pathology, prion-like
Inflammation, metabolism, insulin
Synaptic plastcity & synapse pathology
cellular signalling, kinases, phosphatases, calcium, metal ions
Lysosomes, ubiquitin, proteasome, ER stress, chaperones
Mitochondrial dysfunction, oxidative damage, lipids, lipoproteins, membrane trafficking
Glial cells, neurogenesis, neural networks, plasticity
Vasculature, microbleeds, hypertension, angiogenesis, blood-brain barrier
Neural networks, plasticity
Transcriptional & translational regulation, micro RNAs
Autophagy, apoptosis, cell death
Modeling of disease progression, aging
Therapeutic Targets, Mechanisms for TreatmentAbeta, pGlu-Abeta, tau, phosphorylation, truncation, α-synuclein
Immunotherapy
Secretases, proteases, kinases, other enzymes, ApoE, lipoproteins
Neurotransmitters, dopamine, receptor-based
TREM2 modulators, CD 33 ligands, checkpoint inhibitors​
C​ell transplantation, neurotrophic, synaptic plasticity, repair, regenerative medicine, adult neurogenesis,
Deep brain stimulation
Anti-inflammatory, anti-oxidants
Gene and RNAi therapy
Protein aggregation, misfolding, chaperones
Drug Development, Clinical TrialsImmunotherapy, immunomodulators
Amyloid clearance, clearance of pathologial tau, aggregation inhibitors
Secretase inhibitors & modulators, kinase inhibitors, phosphatase modulators
Neuroprotective & mitochondrial compounds
Neurotransmitter-based modulators, receptor ligands
Vitamins, antioxidants, neuroprotective compounds
Cell-based therapies
Deep brain stimulation, transcranial magnetic stimulation
Medicinal chemistry approaches, drug Repurposing, personalized medicines, regulatory aspects
Non-pharmacological interventions
Imaging, Biomarkers, DiagnosticsStructural MRI, MR spectroscopy
Functional MRI
PET, amyloid, tau, glucose
SPECT
Multimodal imaging
CSF, blood, body fluid biomarkers
EEG, brain mapping, MEG
Cognitive, psychometric & behavioral tests
Genetics, EpidemiologyWhole genome sequencing
Disease-causing mutations
GWAS, genetic associations, susceptibility & protective genes
Aging
Environmental risk factors
Metabolic and cardiovascular
Infectious and inflammation
Other
Cell, Molecular & Systems BiologyAPP, APLP, Abeta, tau, tau isoforms, α-synuclein, ApoE, LRKK2, parkin, PINK1, DJ-1
Secretases, kinases, phosphatases
Posttranslational modifications
Growth factors, synaptic plasticity
GCPR, nicotinic, sigma-1 & other receptors
Network biology, connectome, protein-protein interations
Metabolomics, transcriptomics, lipidomics, proteomics
Epigenetics, histone modification, DNA methylation
Animal ModelsTransgenic rodents
Primates, naturally occuring models
Non-mamalian models
Optogenetics
Dementia, Cognitive & Motor DyfunctionsCaregiver support, mobile applications, social networks, support devices & monitoring
Cognitive training
Motor coordination & exercise
Quality of life 
Functional foods
Behavioral & psychiatric symptoms 
Fall prevention & patient protection​​​​​​​